Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104963 | 0.84 | GPR3 (0.37) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL12888761 | 0.82 | ESR1 (0.33) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL12888819 | 0.82 | ESR1 (0.33) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL92166 | 0.80 | ESR1 (0.44) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL13171745 | 0.76 | GPR3 (0.39) | GPR3MEN1KMT2A | |
| SCHEMBL9915573 | 0.76 | GPR3 (0.39) | GPR3MEN1KMT2A | |
| SCHEMBL1100632 | 0.75 | KMT2A (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL12536406 | 0.71 | ALDH1A1 (0.36) | MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL15146693 | 0.69 | GPR3 (0.40) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL13679292 | 0.69 | GPR3 (0.40) | ESR1ESR2GPR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8152861-B2 | Dark coloured azo dyes | THE PROCTER & GAMBLE COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110225742-A1 | Dark Coloured Azo Dyes | WELLA OPERATIONS US, LLC | 2011-09-22 | — | — | US | disclosed |
| US-7977482-B2 | Dark coloured azo dyes | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-12 | — | — | US | disclosed |
| US-20090118510-A1 | Dark coloured azo dyes | WELLA OPERATIONS US, LLC | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118510-A1 | Dark coloured azo dyes | KRT18, CYB5R3, CYBA | ESR1 3086/4885ESR2 2556/4885GPR3 3943/4885 |
| US-20110225742-A1 | Dark Coloured Azo Dyes | KRT18, CYB5R3, CYBA | ESR1 3086/4885ESR2 2556/4885GPR3 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.