Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014606 | 0.79 | NPC1 (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| Bromide SCHEMBL11839601 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2HTTRAD52 | |
| SCHEMBL11012900 | 0.72 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL2015529 | 0.69 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL14101344 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2HTTRAD52 | |
| SCHEMBL11011214 | 0.68 | CYP1A2 (0.48) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL6253243 | 0.66 | SMN1; SMN2 (0.43) | ALDH1A1MAPTSMN1; SMN2HTTRAD52 | |
| SCHEMBL2750350 | 0.66 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL1748098 | 0.65 | ALDH1A1 (0.66) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL2171106 | 0.64 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2HTTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4535088-A | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1985-08-13 | — | — | US | claimed |
| EP-0111904-A2 | Propynylaminothiazole derivatives | SHIONOGI & CO., LTD. (JP) | 1984-06-27 | — | — | EP | claimed |
| US-4535088-A | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |