Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015120 | 0.83 | CYP3A4 (0.43) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL11014205 | 0.79 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2LMNATP53ALDH1A1 | |
| SCHEMBL11011214 | 0.79 | CYP1A2 (0.48) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL11014071 | 0.78 | GAA (0.44) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL9037879 | 0.78 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL11011390 | 0.78 | LMNA (0.39) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL14554495 | 0.77 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL19371168 | 0.76 | UBE2T (0.51) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL5244847 | 0.75 | HTR1A (0.55) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL11013777 | 0.75 | POLB (0.42) | NPC1RAB9ASMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4535088-A | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1985-08-13 | — | — | US | claimed |
| EP-0111904-A2 | Propynylaminothiazole derivatives | SHIONOGI & CO., LTD. (JP) | 1984-06-27 | — | — | EP | claimed |
| US-4535088-A | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| EP-0111904-A2 | Propynylaminothiazole derivatives | SHIONOGI & CO., LTD. (JP) | 1984-06-27 | — | — | EP | disclosed |