SCHEMBL1748098

SCHEMBL1748098

Cc1nc2c(C)cccc2s1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.66
MAPT P10636 5/20 0.50
PKM P14618 1/20 0.47
GAA P10253 2/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
KDM4E B2RXH2 3/20 0.43
ALOX15 P16050 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 2/20 0.43
USP2 O75604 1/20 0.43
MCL1 Q07820 1/20 0.43
ESR2 Q92731 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL1770191 0.98 ALDH1A1 (0.63) ALDH1A1MAPTPKMGAANPC1
Hydrochloric Acid SCHEMBL28519025 0.96 ALDH1A1 (0.61) ALDH1A1MAPTPKMGAANPC1
Formamide SCHEMBL28482328 0.89 ALDH1A1 (0.59) ALDH1A1MAPTPKMGAANPC1
SCHEMBL3918916 0.81 ALDH1A1 (0.63) ALDH1A1MAPTPKMGAANPC1
SCHEMBL14127197 0.81 ALDH1A1 (0.63) ALDH1A1MAPTPKMGAANPC1
SCHEMBL546270 0.79 ALDH1A1 (0.61) ALDH1A1MAPTPKMGAANPC1
SCHEMBL2615997 0.79 LMNA (0.61) ALDH1A1MAPTPKMGAANPC1
SCHEMBL5893122 0.79 ALDH1A1 (0.61) ALDH1A1MAPTPKMGAANPC1
SCHEMBL316414 0.79 ALDH1A1 (0.43) ALDH1A1MAPTPKMGAANPC1
SCHEMBL21845482 0.79 ALDH1A1 (0.43) ALDH1A1MAPTPKMGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264097-A Fluorescent probe for monitoring FAO level of living cells and macrophage polarization phenotype, and preparation method and application thereof 贵州医科大学 2025-01-07 CN claimed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO claimed
CN-104419326-A Slurry composition for chemical mechanical polishing COWON INNOTECH INC 2015-03-18 CN claimed
EP-2493893-B1 AZABICYCLO[2.2.1]HEPTANE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS BRISTOL MYERS SQUIBB CO (US) 2014-01-15 EP claimed
CN-103251513-A Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition OREAL 2013-08-21 CN claimed
CN-102659775-A Fluorescence probe for detecting thiol compounds, preparation method and application thereof UNIV SOOCHOW 2012-09-12 CN claimed
CN-101922026-B Methanesulfonic acid-based matte pure tin electroplating solution and additive thereof DILIGENCE TECHNOLOGY CO LTD 2012-02-01 CN claimed
CN-101922026-A Methanesulfonic acid-based matte pure tin electroplating solution and additive thereof DILIGENCE TECHNOLOGY CO LTD 2010-12-22 CN claimed
CN-101802107-A Dye composition comprising at least one colourless disulfide/thiol precursor and dyeing process using said composition OREAL 2010-08-11 CN claimed
JP-6220028-A None JP disclosed
US-12384789-B2 Compounds for treating Huntington's disease PTC THERAPEUTICS, INC. (US) 2025-08-12 US disclosed
CN-119264097-A Fluorescent probe for monitoring FAO level of living cells and macrophage polarization phenotype, and preparation method and application thereof 贵州医科大学 2025-01-07 CN disclosed
WO-2024200263-A1 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS α-SYNUCLEIN BINDING COMPOUNDS EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2024-10-03 WO disclosed
EP-4438597-A1 2-STYRYLBENZOTHIAZOLE DERIVATIVES AS A-SYNUCLEIN BINDING COMPOUNDS Eberhard Karls Universität Tübingen Medizinische Fakultät (DE) 2024-10-02 EP disclosed
EP-0455545-A1 Process for the preparation of mono- or polyalkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-11-06 EP disclosed
EP-0395388-A2 Image forming method KONICA CORPORATION (JP) 1990-10-31 EP disclosed
EP-0214423-B1 PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED BENZOTHIAZOLES HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-03 EP disclosed
US-4727154-A ACRYLATION 2-MERCAPTOPHENYLUREA HOECHST AKTIENGESELLSCHAFT 1988-02-23 US disclosed
EP-0214423-A1 Process for the preparation of 2-substituted benzothiazoles HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-18 EP disclosed
US-3994733-A CYANINE DYES, A BENZOTHIAZOLE, OR BENZOTHIAZOLONE, OR NAPHTHOTHIAZOLE, OR NAPHTHOTHIAZOLONE, OR A QUINOLONE FUJI PHOTO FILM CO., LTD. (JA) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384789-B2 Compounds for treating Huntington's disease HTT, HYPK, FH ALDH1A1 1524/4885MAPT 15/4885PKM 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.