Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439465 | 0.86 | HDAC4 (0.71) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL441932 | 0.86 | HDAC4 (0.67) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL7093999 | 0.84 | ALDH1A1 (0.58) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL13233238 | 0.84 | HDAC4 (0.65) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL5142374 | 0.83 | ALDH1A1 (0.66) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL9789930 | 0.83 | MAPK1 (0.66) | L3MBTL1CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL4188909 | 0.83 | NLRP3 (0.59) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL2885788 | 0.83 | NLRP3 (0.64) | CYP1A2ALDH1A1HDAC4NLRP3MAPT | |
| SCHEMBL29720309 | 0.83 | NLRP3 (0.59) | CYP1A2MEN1KMT2AALDH1A1HDAC4 | |
| SCHEMBL19615542 | 0.82 | NLRP3 (0.55) | CYP1A2MEN1KMT2AALDH1A1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4550172-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |