Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101374 | 0.98 | NPSR1 (0.40) | NPSR1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL28404482 | 0.76 | LMNA (0.36) | NPSR1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6270795 | 0.70 | DPP4 (0.40) | NPSR1 | |
| SCHEMBL461574 | 0.69 | — | — | |
| SCHEMBL7063134 | 0.69 | PDPK1 (0.37) | — | |
| SCHEMBL6842093 | 0.68 | NPSR1 (0.47) | NPSR1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL669005 | 0.67 | PNP (0.59) | NPSR1ALDH1A1HPGD | |
| SCHEMBL786949 | 0.67 | NPSR1 (0.50) | NPSR1ALDH1A1 | |
| SCHEMBL391560 | 0.65 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL36982 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153787-B2 | Azacytosine derivatives useful as antiviral agents | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2012-04-10 | — | — | US | disclosed |
| EP-1966226-B1 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | LEUVEN K U RES & DEV (BE) | 2010-11-10 | — | — | EP | disclosed |
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | ITPA, ZC3HAV1, MTAP | NPSR1 4759/4885L3MBTL1 4397/4885ALDH1A1 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.