Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.93 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CDC42 | P60953 | 1/20 | 0.55 |
| ▸ | RAC1 | P63000 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naproxol SCHEMBL8471214 | 0.97 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL30599771 | 0.97 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL29979997 | 0.97 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL10395753 | 0.97 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL43203 | 0.97 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL9451481 | 0.88 | ABCB11 (0.82) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL15701616 | 0.82 | ABCB11 (0.62) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5673091 | 0.82 | ABCB11 (0.64) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL5673083 | 0.82 | ABCB11 (0.64) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL11017004 | 0.81 | ABCB11 (0.63) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149588-A2 | N-(naphthyl-alkyl)-hydroxylamines | SANDOZ AG (CH) | 1985-07-24 | — | — | EP | disclosed |