Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CDC42 | P60953 | 1/20 | 0.58 |
| ▸ | RAC1 | P63000 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naproxol SCHEMBL10395753 | 1.00 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL30599771 | 1.00 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL43203 | 1.00 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL8471214 | 1.00 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL11015086 | 0.97 | ABCB11 (0.93) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| Naproxol SCHEMBL9451481 | 0.91 | ABCB11 (0.82) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL9009741 | 0.84 | ABCB11 (0.72) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL28346869 | 0.84 | ABCB11 (0.72) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL14783039 | 0.83 | ABCB11 (0.71) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL11806102 | 0.83 | ABCB11 (0.71) | ABCB11AKR1C3AKR1C2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160123-B | Method for preparing carboxylic acid compound by oxidizing alcohol by using oxygen as oxidant under catalysis of copper | 复旦大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-115160123-A | Method for preparing carboxylic acid compound by oxidizing alcohol with oxygen as oxidant under catalysis of copper | 复旦大学 | 2022-10-11 | — | — | CN | disclosed |