Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834971 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KMT2ABCHEACHEHSP90AA1 | |
| SCHEMBL11878095 | 0.75 | MAPT (0.45) | MAPTALDH1A1HPGDALOX12TDP1 | |
| SCHEMBL11010577 | 0.72 | POLB (0.38) | TP53KMT2AHSP90AA1HSP90AB1S1PR1 | |
| SCHEMBL9835639 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GAABCHEACHEHSP90AA1 | |
| SCHEMBL11014211 | 0.71 | KDM4E (0.38) | TDP1KMT2AKDM4EMEN1S1PR1 | |
| SCHEMBL7499167 | 0.69 | USP2 (0.45) | TDP1KMT2AMEN1POLB | |
| SCHEMBL20829215 | 0.68 | POLB (0.37) | MAPTALDH1A1HPGDALOX12TDP1 | |
| SCHEMBL22413756 | 0.67 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDALOX12TDP1 | |
| SCHEMBL22413671 | 0.67 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDALOX12TDP1 | |
| SCHEMBL11012750 | 0.66 | KIT (0.36) | ALDH1A1HPGDTDP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547496-A | Antiulcer [1] benzepino[3,4-b]pyridine and compositions | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-10-15 | — | — | US | disclosed |