Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 6/20 | 0.54 |
| ▸ | PDE4A | P27815 | 6/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202302 | 0.76 | PDE5A (0.48) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7345942 | 0.76 | PDE5A (0.62) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7345938 | 0.76 | PDE5A (0.66) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27164821 | 0.73 | PNP (0.32) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27164823 | 0.71 | HSD17B10 (0.41) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL11036035 | 0.70 | ALDH1A1 (0.40) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1546788 | 0.70 | ALDH1A1 (0.54) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26907658 | 0.70 | XDH (0.32) | SMN1; SMN2TLR7 | |
| SCHEMBL1943792 | 0.70 | ALDH1A1 (0.54) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Cipamfylline SCHEMBL26990 | 0.70 | PDE4A (1.00) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154906-A2 | 3-Cyclopropylmethyl-1,3,5-triazine-2,4-dione | BAYER AG (DE) | 1985-09-18 | — | — | EP | claimed |