Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036058 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HPGDRECQLMEN1KMT2A | |
| SCHEMBL11016276 | 0.70 | PDE5A (0.54) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL9247800 | 0.63 | ALDH1A1 (0.50) | ALDH1A1HPGDRECQLMEN1KMT2A | |
| SCHEMBL11240482 | 0.61 | MTOR (0.40) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL20226431 | 0.59 | CYP3A4 (0.64) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL19566355 | 0.59 | CYP3A4 (0.64) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL24191327 | 0.59 | SCN9A (0.56) | ALDH1A1MEN1KMT2ALMNARAB9A | |
| SCHEMBL10823255 | 0.59 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL17767280 | 0.57 | ALDH1A1 (0.47) | ALDH1A1HPGDRECQLMEN1KMT2A | |
| SCHEMBL5755833 | 0.57 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154906-A2 | 3-Cyclopropylmethyl-1,3,5-triazine-2,4-dione | BAYER AG (DE) | 1985-09-18 | — | — | EP | claimed |
| EP-0154906-A2 | 3-Cyclopropylmethyl-1,3,5-triazine-2,4-dione | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |