Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649932 | 0.84 | TTR (0.40) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL4650519 | 0.84 | HPGDS (0.45) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10777078 | 0.82 | TIMP3 (0.40) | HPGDSCASP6KDM4ENSD2ALDH1A1 | |
| SCHEMBL7899594 | 0.74 | CDK2 (0.42) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10779303 | 0.73 | SNCA (0.44) | CCNA2CDK2JAK2JAK3PTK2 | |
| SCHEMBL285816 | 0.73 | HPGDS (0.57) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11426909 | 0.73 | CDK2 (0.44) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8055072 | 0.73 | TSHR (0.57) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL8057706 | 0.73 | TTR (0.44) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL4649879 | 0.71 | TSHR (0.38) | HPGDSJAK2JAK3PTK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135381-A1 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-27 | — | — | EP | disclosed |