Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 3/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754997 | 0.91 | C1R (0.52) | C1RFBP1ELANEADORA3KDM4E | |
| SCHEMBL10748148 | 0.80 | ELANE (0.65) | C1RELANEKDM4EALDH1A1 | |
| SCHEMBL11772430 | 0.73 | GSK3B (0.58) | FBP1POLBGAAADORA3KDM4E | |
| SCHEMBL14697189 | 0.73 | ANO1 (0.61) | FBP1POLBGAACASP3SENP7 | |
| SCHEMBL3453029 | 0.72 | NPC1 (0.71) | C1RGAAELANEKDM4EALDH1A1 | |
| SCHEMBL4866482 | 0.72 | CSNK1D (0.52) | FBP1POLBGAAANO1 | |
| SCHEMBL6350945 | 0.71 | C1R (0.46) | C1RELANEKDM4EALDH1A1 | |
| SCHEMBL6567397 | 0.70 | ALDH1A1 (0.48) | C1RPOLBELANEKDM4EALDH1A1 | |
| SCHEMBL1812732 | 0.70 | ELANE (0.70) | C1RELANEKDM4EALDH1A1 | |
| SCHEMBL31000399 | 0.70 | ELANE (0.70) | C1RELANEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |