SCHEMBL6567397

SCHEMBL6567397

CCC(c1nc2ccc(Cl)cc2c(=O)o1)c1nc2ccc(Cl)cc2c(=O)o1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 4/20 0.48
C1R P00736 3/20 0.48
HTT P42858 1/20 0.47
ELANE P08246 7/20 0.45
APEX1 P27695 1/20 0.41
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
FABP3 P05413 1/20 0.38
FABP4 P15090 1/20 0.38
FABP5 Q01469 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566279 0.90 ELANE (0.47) ALDH1A1KDM4EC1RHTTELANE
SCHEMBL3817466 0.85 C1R (0.53) ALDH1A1KDM4EC1RHTTELANE
SCHEMBL6565611 0.84 ELANE (0.62) ALDH1A1KDM4EC1RHTTELANE
SCHEMBL6565334 0.82 KDM4E (0.47) ALDH1A1KDM4EC1RHTTELANE
SCHEMBL6565648 0.82 ELANE (0.48) ALDH1A1KDM4EHTTELANEMEN1
SCHEMBL6565217 0.82 MAPT (0.47) ALDH1A1KDM4EHTTELANEMEN1
SCHEMBL6567161 0.82 TP53 (0.51) ALDH1A1KDM4EHTTELANEMEN1
SCHEMBL6567413 0.80 KDM4E (0.54) ALDH1A1KDM4EC1RHTTPOLB
SCHEMBL6565065 0.80 KDM4E (0.45) ALDH1A1KDM4EHTTELANE
SCHEMBL6567394 0.80 ELANE (0.49) ALDH1A1KDM4EC1RHTTELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed