SCHEMBL11018367

SCHEMBL11018367

NC(=O)c1ccc2c(c1)nnn2[Ag]

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.53
HCAR3 P49019 10/20 0.47
KMT2A Q03164 1/20 0.46
FGFR1 P11362 1/20 0.46
HPGD P15428 3/20 0.44
HCAR2 Q8TDS4 1/20 0.44
JAK2 O60674 3/20 0.43
JAK1 P23458 3/20 0.43
TYK2 P29597 3/20 0.43
JAK3 P52333 3/20 0.43
KDM4E B2RXH2 1/20 0.42
BRD4 O60885 1/20 0.42
ALDH1A1 P00352 1/20 0.42
BRPF1 P55201 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8424378 0.85 HCAR3 (0.66) HCAR3HPGDHCAR2
SCHEMBL29751005 0.80 HCAR3 (0.73) NAMPTHCAR3KMT2AHPGDKDM4E
SCHEMBL21409085 0.80 HCAR3 (0.73) NAMPTHCAR3KMT2AHPGDKDM4E
SCHEMBL30807488 0.76 NAMPT (0.53) NAMPTHCAR3KMT2AFGFR1HPGD
SCHEMBL20588071 0.76 HCAR3 (0.76) NAMPTHCAR3KMT2AFGFR1HPGD
SCHEMBL8421911 0.73 KDM4E (0.54) KMT2AFGFR1KDM4EALDH1A1SMN1; SMN2
SCHEMBL10348181 0.73 ALDH1A1 (0.41) HCAR3KMT2AFGFR1HPGDHCAR2
SCHEMBL29751355 0.70 HCAR3 (0.55) NAMPTHCAR3KMT2AHPGDKDM4E
SCHEMBL8423882 0.70 HDAC6 (0.36) HCAR3KMT2AHPGDKDM4EALDH1A1
SCHEMBL10347621 0.70 MAPT (0.55) KMT2AHPGDKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0157639-A2 Heat-developable multilayered color photo-sensitive material KONICA CORPORATION (JP) 1985-10-09 EP disclosed