SCHEMBL10348181

SCHEMBL10348181

Oc1ccc2c(c1)nnn2[Ag]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
FGFR1 P11362 1/20 0.39
ENPP2 Q13822 1/20 0.36
PKM P14618 1/20 0.36
HCAR3 P49019 4/20 0.35
RAD51 Q06609 1/20 0.35
TNKS O95271 1/20 0.34
PARP1 P09874 1/20 0.34
PARP15 Q460N3 1/20 0.34
PARP14 Q460N5 1/20 0.34
PARP10 Q53GL7 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PARP11 Q9NR21 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
PARP4 Q9UKK3 1/20 0.34
PARP3 Q9Y6F1 1/20 0.34
AURKA O14965 1/20 0.34
CTNNB1 P35222 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16863946 0.78 PKM (0.58) ALDH1A1HPGDKDM4EFGFR1ENPP2
SCHEMBL9636128 0.76 PABPC1 (0.36) ALDH1A1KDM4EPKMHCAR3AURKA
SCHEMBL6743405 0.76 KCNMA1 (0.44) ALDH1A1FGFR1HCAR3MEN1KMT2A
SCHEMBL1150909 0.76 CHEK1 (0.50) KDM4EFGFR1MEN1KMT2AKEAP1
SCHEMBL3182817 0.76 HCAR3 (0.59) ALDH1A1HPGDKDM4EHCAR3MEN1
Water SCHEMBL5279559 0.76 PKM (0.56) ALDH1A1HPGDKDM4EFGFR1ENPP2
SCHEMBL8423882 0.73 HDAC6 (0.36) ALDH1A1HPGDKDM4EHCAR3MEN1
SCHEMBL31257493 0.72 HCAR3 (0.46) ALDH1A1HPGDKDM4EFGFR1HCAR3
SCHEMBL31257477 0.72 PKM (0.44) ALDH1A1HPGDKDM4EFGFR1ENPP2
SCHEMBL31257519 0.72 HCAR3 (0.62) HCAR3RPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 EP disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 US disclosed
EP-0157639-A2 Heat-developable multilayered color photo-sensitive material KONICA CORPORATION (JP) 1985-10-09 EP disclosed
US-4543309-A BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-24 US disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 EP disclosed