SCHEMBL1612973

SCHEMBL1612973

O=c1nc(S)[nH]c(=O)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17671749 0.67 MAPT (0.46)
SCHEMBL31495235 0.67
SCHEMBL11018441 0.67
SCHEMBL3587857 0.67
SCHEMBL11705280 0.65 MAPT (0.45)
SCHEMBL16544560 0.62 LMNA (0.40)
Oteracil SCHEMBL464773 0.62 LMNA (1.00)
SCHEMBL5321890 0.62 L3MBTL1 (0.42)
SCHEMBL9781236 0.62 LMNA (0.40)
Oteracil SCHEMBL4648864 0.60 LMNA (0.95)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10683413-B2 Polyacetal resin composition and sliding member POLYPLASTICS CO., LTD. (JP) 2020-06-16 US disclosed
EP-3202847-B1 POLYACETAL RESIN COMPOSITION AND SLIDING MEMBER POLYPLASTICS CO (JP) 2019-02-20 EP disclosed
US-20170306140-A1 POLYACETAL RESIN COMPOSITION AND SLIDING MEMBER POLYPLASTICS CO., LTD. (JP) 2017-10-26 US disclosed
US-20170306141-A1 POLYACETAL RESIN COMPOSITION AND SLIDING MEMBER POLYPLASTICS CO., LTD. (JP) 2017-10-26 US disclosed
US-20170283608-A1 POLYACETAL RESIN COMPOSITION AND SLIDING MEMBER POLYPLASTICS CO., LTD. (JP) 2017-10-05 US disclosed
EP-3202845-A1 POLYACETAL RESIN COMPOSITION AND SLIDING MEMBER Polyplastics Co., Ltd. (JP) 2017-08-09 EP disclosed
EP-3202847-A1 POLYACETAL RESIN COMPOSITION AND SLIDING MEMBER Polyplastics Co., Ltd. (JP) 2017-08-09 EP disclosed
US-9573908-B2 Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2017-02-21 US disclosed
US-20150126474-A1 BROAD SPECTRUM PRO-QUORUM-SENSING MOLECULES AS INHIBITORS OF VIRULENCE IN VIBRIOS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-05-07 US disclosed
WO-2014092751-A1 BROAD SPECTRUM PRO-QUORUM-SENSING MOLECULES AS INHIBITORS OF VIRULENCE IN VIBRIOS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-06-19 WO disclosed
US-20110086952-A1 POLYACETAL RESIN MOLDED ARTICLE HAVING EXCELLENT ACID RESISTANCE POLYPLASTICS CO. LTD. 2011-04-14 US disclosed
US-20090143508-A1 POLYACETAL RESIN MOLDED ARTICLE HAVING EXCELLENT ACID RESISTANCE POLYPLASTICS CO., LTD. (JP) 2009-06-04 US disclosed
EP-2065434-A2 Polyacetal resin molded article having excellent acid resistance Polyplastics Co., Ltd. (JP) 2009-06-03 EP disclosed
EP-0814122-B1 Polyacetal resin composition POLYPLASTICS CO (JP) 2006-03-29 EP disclosed
US-6136902-A EXCELLENT CORROSION INHIBITING EFFECT ON METALS, PARTICULARLY REDUCED IN THE ADVERSE EFFECT ON MAGNETIC TAPES OR THE LIKE, POLYPLASTICS CO., LTD. (JP) 2000-10-24 US disclosed
EP-0814122-A1 Polyacetal resin composition POLYPLASTICS CO. LTD. (JP) 1997-12-29 EP disclosed