Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022085 | 0.83 | LMNA (0.50) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL11856958 | 0.78 | ATM (0.45) | LMNAMETAP2IDO1TDO2MGLL | |
| SCHEMBL11472432 | 0.77 | MAPT (0.43) | LMNATP53HTTMETAP2IDO1 | |
| SCHEMBL17513258 | 0.76 | TP53 (0.53) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL14677340 | 0.75 | TP53 (0.61) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL11853400 | 0.72 | L3MBTL1 (0.51) | LMNAMETAP2L3MBTL1ATMMEN1 | |
| SCHEMBL14981213 | 0.72 | TP53 (0.57) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL10396654 | 0.72 | TP53 (0.57) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL15129327 | 0.72 | TP53 (0.57) | LMNATP53HTTIDO1TDO2 | |
| SCHEMBL1143487 | 0.72 | TP53 (0.62) | LMNATP53HTTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536599-A | HYDROLYZING THE NITRILE DERIVATIVE TO THE AMIDE USING AN ORGANIC QUATERNARY AMINE SALT CATALYST; EFFICIENCY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0008532-B1 | SYNTHESIS OF AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-20 | — | — | EP | disclosed |
| EP-0008532-A1 | Synthesis of amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-05 | — | — | EP | disclosed |