Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16844047 | 0.78 | PDE3B (0.43) | NSD2MAOAMAOBCFTR | |
| SCHEMBL27440272 | 0.78 | CYP1A1 (0.47) | CYP1A1CYP1B1KDM1ACA12CA1 | |
| SCHEMBL15499138 | 0.77 | CYP1A1 (0.46) | CYP1A1CYP1B1KDM1ATSHRCA12 | |
| SCHEMBL17239835 | 0.77 | CHEK1 (0.51) | CYP1A1CYP1B1KDM1AARCTDSP1 | |
| SCHEMBL13039489 | 0.75 | TRPA1 (0.47) | CYP1A1CYP1B1KDM1ACA12CA1 | |
| SCHEMBL279606 | 0.75 | ALDH1A1 (0.51) | CYP1A1CYP1B1KDM1ATSHRCA12 | |
| SCHEMBL2570411 | 0.74 | AR (0.53) | CYP1A1CYP1B1KDM1AARMAOA | |
| SCHEMBL16844161 | 0.74 | MMP3 (0.52) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL1436484 | 0.74 | FYN (0.56) | KDM1AARMAOAMAOB | |
| SCHEMBL10760601 | 0.73 | MAPK10 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |