Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12736511 | 0.81 | MAPT (0.42) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19389699 | 0.81 | RORC (0.33) | NPC1RAB9AMAPK1RORCTSHR | |
| SCHEMBL13523936 | 0.79 | NPC1 (0.40) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19333098 | 0.78 | NPC1 (0.33) | MAPTNPC1RAB9AMAPK1RORC | |
| SCHEMBL3151324 | 0.77 | MAPT (0.49) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL24022682 | 0.77 | HRH3 (0.44) | ALDH1A1GAACYP1A2CYP2C19ESR1 | |
| SCHEMBL11027787 | 0.76 | CNR2 (0.47) | MAPTNPC1RAB9ACNR1CNR2 | |
| SCHEMBL582676 | 0.74 | NPC1 (0.77) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL12736603 | 0.73 | ALDH1A1 (0.42) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL14487139 | 0.72 | MAPT (0.43) | MAPTNPC1RAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069065-B1 | PROCESS FOR THE ALKYLATION OR ARALKYLATION OF AROMATIC AMINES | CIBA-GEIGY AG (CH) | 1985-02-13 | — | — | EP | disclosed |
| EP-0069065-A1 | Process for the alkylation or aralkylation of aromatic amines | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |