Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.36 |
| ▸ | SELP | P16109 | 3/20 | 0.34 |
| ▸ | SELL | P14151 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026178 | 0.81 | KDM4E (0.43) | LMNA | |
| SCHEMBL8469123 | 0.81 | KDM4E (0.43) | LMNA | |
| SCHEMBL15664683 | 0.76 | TET3 (0.42) | KMT2AL3MBTL1SLC6A4SLC6A3 | |
| SCHEMBL15664899 | 0.73 | DRD2 (0.43) | MEN1KMT2A | |
| SCHEMBL10483428 | 0.70 | ESR2 (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10659448 | 0.70 | AKR1C1 (0.48) | LMNAMEN1KMT2A | |
| SCHEMBL435512 | 0.70 | AKR1C1 (0.48) | LMNAMEN1KMT2A | |
| SCHEMBL994596 | 0.70 | AKR1C1 (0.48) | LMNAMEN1KMT2A | |
| SCHEMBL38656246 | 0.69 | CA12 (0.57) | LMNAMEN1KMT2ACYP19A1CYP11B1 | |
| SCHEMBL5693936 | 0.69 | CA12 (0.57) | LMNAMEN1KMT2ACYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163338-A1 | Process for preparing naproxen | Nobel Chemicals AB (SE) | 1985-12-04 | — | — | EP | disclosed |