Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.42 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469123 | 0.88 | KDM4E (0.43) | CYP2C19ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8026178 | 0.88 | KDM4E (0.43) | CYP2C19ALDH1A1KDM4EMAPK1 | |
| SCHEMBL10483428 | 0.81 | ESR2 (0.41) | CYP3A4CYP2C19CA1CA2SLC6A4 | |
| SCHEMBL15664899 | 0.81 | DRD2 (0.43) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL10659448 | 0.80 | AKR1C1 (0.48) | KMT2AOPRM1ALDH1A1HSD11B1GRIN1 | |
| SCHEMBL994596 | 0.80 | AKR1C1 (0.48) | KMT2AOPRM1ALDH1A1HSD11B1GRIN1 | |
| SCHEMBL435512 | 0.80 | AKR1C1 (0.48) | KMT2AOPRM1ALDH1A1HSD11B1GRIN1 | |
| Hydrochloric Acid SCHEMBL8114401 | 0.79 | AKR1C1 (0.47) | KMT2AOPRM1ALDH1A1HSD11B1GRIN1 | |
| Hydrochloric Acid SCHEMBL8114403 | 0.79 | AKR1C1 (0.47) | KMT2AOPRM1ALDH1A1HSD11B1GRIN1 | |
| SCHEMBL11241224 | 0.78 | AKR1C1 (0.40) | CYP2C19ALDH1A1SMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127762-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED PROLINE | API CORPORATION (JP) | 2014-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127762-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED PROLINE | PREP, NPEPPS, DNPEP | TET3 1263/4885KMT2A 1129/4885FBXL19 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.