Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CDC42 | P60953 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469123 | 1.00 | KDM4E (0.43) | KDM4ELMNAAKR1C3AKR1C2PTGS1 | |
| SCHEMBL15664683 | 0.88 | TET3 (0.42) | KDM4EALDH1A1CYP2C19MAPK1 | |
| SCHEMBL11019253 | 0.81 | LMNA (0.38) | LMNA | |
| SCHEMBL15546631 | 0.76 | KDM4E (0.51) | KDM4ELMNAAKR1C3AKR1C2PTGS1 | |
| SCHEMBL8589035 | 0.75 | KMT2A (0.52) | KDM4ELMNAAKR1C3AKR1C2PTGS1 | |
| SCHEMBL15664899 | 0.72 | DRD2 (0.43) | TSHRALDH1A1 | |
| SCHEMBL10483428 | 0.72 | ESR2 (0.41) | CYP2C19AKR1C1 | |
| SCHEMBL10448280 | 0.72 | ADAM17 (0.44) | AKR1C3PTGS1ALDH1A1HPGDMAPK1 | |
| SCHEMBL994596 | 0.72 | AKR1C1 (0.48) | LMNAALDH1A1AKR1C1 | |
| SCHEMBL10659448 | 0.72 | AKR1C1 (0.48) | LMNAALDH1A1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035641-B1 | CYSTEIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | ALFA FARMACEUTICI S.p.A. (IT) | 1984-04-25 | — | — | EP | claimed |
| EP-0089711-A2 | Process for preparing esters of 2-(6'-methoxy-2'-naphthyl)-propionic acid | BLASCHIM S.p.A. (IT) | 1983-09-28 | — | — | EP | claimed |
| EP-0022529-B1 | PROCESS FOR THE RESOLUTION OF D,L 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE D AND L ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE D ACID; A SALT OF THE D ACID | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-29 | — | — | EP | claimed |
| EP-0035641-A2 | Cystein derivatives, process for their preparation and medicines containing them | ALFA FARMACEUTICI S.p.A. (IT) | 1981-09-16 | — | — | EP | claimed |
| EP-0973714-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998030528-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| EP-0035641-A2 | Cystein derivatives, process for their preparation and medicines containing them | ALFA FARMACEUTICI S.p.A. (IT) | 1981-09-16 | — | — | EP | disclosed |