Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 13/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019284 | 0.92 | CHEK2 (0.55) | CHEK2 | |
| SCHEMBL11017892 | 0.91 | MAPT (0.44) | CHEK2MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL11018637 | 0.90 | ALDH1A1 (0.44) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL11020402 | 0.89 | CHEK2 (0.47) | CHEK2KDM4EALDH1A1 | |
| SCHEMBL11018192 | 0.88 | MAPT (0.48) | CHEK2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL11018864 | 0.86 | CHEK2 (0.48) | CHEK2 | |
| SCHEMBL11017899 | 0.83 | CHEK2 (0.50) | CHEK2MAPTNPC1RAB9ATP53 | |
| SCHEMBL11018668 | 0.82 | KDM4E (0.48) | CHEK2MAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL10748970 | 0.81 | CHEK2 (0.51) | CHEK2 | |
| SCHEMBL11018857 | 0.81 | MAPT (0.44) | MAPTKDM4EALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |