Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019277 | 0.92 | CHEK2 (0.46) | CHEK2 | |
| SCHEMBL11017899 | 0.91 | CHEK2 (0.50) | CHEK2 | |
| SCHEMBL11018668 | 0.90 | KDM4E (0.48) | CHEK2 | |
| SCHEMBL11020406 | 0.89 | CHEK2 (0.56) | CHEK2 | |
| SCHEMBL11018196 | 0.88 | CHEK2 (0.51) | CHEK2 | |
| SCHEMBL11017892 | 0.83 | MAPT (0.44) | CHEK2 | |
| SCHEMBL11018637 | 0.82 | ALDH1A1 (0.44) | — | |
| SCHEMBL11018866 | 0.81 | MAPT (0.44) | CHEK2 | |
| SCHEMBL11020402 | 0.81 | CHEK2 (0.47) | CHEK2 | |
| SCHEMBL11017842 | 0.81 | CHEK2 (0.52) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |