Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019878 | 0.78 | CYP2A13 (0.55) | CYP2A13MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL22946312 | 0.75 | CYP2A13 (0.58) | CYP2A13L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22946195 | 0.75 | CYP2A13 (0.58) | CYP2A13L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL30424191 | 0.75 | CYP2A13 (0.58) | CYP2A13L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL30423757 | 0.75 | CYP2A13 (0.58) | CYP2A13L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL11019683 | 0.74 | CYP2A13 (0.51) | CYP2A13L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL22946201 | 0.74 | HCRTR1 (0.57) | CYP2A13L3MBTL1CNR1MEN1KMT2A | |
| SCHEMBL11018569 | 0.71 | KDM4E (0.53) | L3MBTL1ALDH1A1NPC1RAB9AHCRTR1 | |
| SCHEMBL11036675 | 0.70 | KDM4E (0.47) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL11023596 | 0.69 | CTSB (0.65) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | claimed |
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | disclosed |