Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018569 | 0.72 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL745085 | 0.72 | ABCB1 (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL16884075 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL11019307 | 0.70 | CYP2A13 (0.49) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL7029785 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL148489 | 0.69 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL28300187 | 0.68 | HTT (0.50) | KDM4EALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL11019683 | 0.68 | CYP2A13 (0.51) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL20006950 | 0.68 | PTPN1 (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2TSHR | |
| SCHEMBL7370799 | 0.67 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | claimed |
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | disclosed |