Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020085 | 1.00 | RAB9A (0.45) | RAB9ASMN1; SMN2PKMRECQLNPC1 | |
| SCHEMBL11015932 | 0.81 | SMN1; SMN2 (0.62) | RAB9ASMN1; SMN2PKMRECQLNPC1 | |
| SCHEMBL11015933 | 0.81 | SMN1; SMN2 (0.62) | RAB9ASMN1; SMN2PKMRECQLNPC1 | |
| SCHEMBL11018276 | 0.78 | PDE3B (0.67) | RAB9ASMN1; SMN2PKMNPC1PDE3B | |
| SCHEMBL11018273 | 0.78 | PDE3B (0.67) | RAB9ASMN1; SMN2PKMNPC1PDE3B | |
| SCHEMBL11021355 | 0.78 | RAB9A (0.49) | RAB9ASMN1; SMN2PKMRECQLNPC1 | |
| SCHEMBL11021347 | 0.78 | RAB9A (0.49) | RAB9ASMN1; SMN2PKMRECQLNPC1 | |
| SCHEMBL11048182 | 0.73 | PDE3B (0.34) | PDE3BPDE3ACYP11B1CYP11B2CRBN | |
| SCHEMBL11048184 | 0.73 | PDE3B (0.34) | PDE3BPDE3ACYP11B1CYP11B2CRBN | |
| SCHEMBL10365507 | 0.71 | IDO1 (0.44) | CYP11B1CYP11B2IDO1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150463-A1 | Substituted 4.5-dihydro-6-vinyl-3(2H)-pyridazinones and 6-vinyl-3(2H)-pyridazinones and process for producing the same | A. Nattermann & Cie. GmbH (DE) | 1985-08-07 | — | — | EP | disclosed |