Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853066 | 0.82 | SOAT1 (0.49) | ALDH1A1KDM4EPTPN1 | |
| SCHEMBL11021692 | 0.82 | L3MBTL1 (0.44) | ALDH1A1KDM4ETDP1PTPN1HTR7 | |
| SCHEMBL11022587 | 0.81 | RAB9A (0.50) | ALDH1A1KDM4ETDP1HTR7 | |
| SCHEMBL22280679 | 0.78 | RAB9A (0.48) | KDM4EHTR7 | |
| SCHEMBL2573003 | 0.78 | PTPN1 (0.49) | ALDH1A1KDM4ETDP1PTPN1SCN1A | |
| SCHEMBL10675332 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1SIGMAR1ACHE | |
| SCHEMBL10680033 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4ETDP1SIGMAR1ACHE | |
| SCHEMBL2570181 | 0.77 | CYP19A1 (0.54) | ALDH1A1KDM4ETDP1PTPN1SCN1A | |
| Hydrochloric Acid SCHEMBL11617772 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4ESCN1ASCN2ASCN3A | |
| SCHEMBL25852986 | 0.76 | RAB9A (0.63) | ALDH1A1KDM4ETDP1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |