Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22805528 | 0.83 | VDR (0.51) | VDRALDH1A1KDM4EHPGDMMP2 | |
| SCHEMBL14572925 | 0.83 | VDR (0.51) | VDRALDH1A1KDM4EHPGDMMP2 | |
| SCHEMBL31004989 | 0.81 | MMP2 (0.53) | VDRALDH1A1HPGDMMP2MMP9 | |
| SCHEMBL14318318 | 0.81 | VDR (0.52) | VDRALDH1A1KDM4EHPGDMMP2 | |
| SCHEMBL10391190 | 0.81 | KMT2A (0.43) | ALDH1A1HPGDMAPTKMT2AMAPK1 | |
| SCHEMBL12802775 | 0.80 | VDR (0.48) | VDRALDH1A1KDM4EHPGDMMP2 | |
| SCHEMBL28367938 | 0.77 | KMT2A (0.57) | VDRALDH1A1KDM4EHPGDMMP2 | |
| SCHEMBL4582326 | 0.76 | VDR (0.49) | VDRALDH1A1KDM4EHPGDMMP2 | |
| SCHEMBL5830519 | 0.75 | GBA1 (0.46) | VDRALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL10932836 | 0.75 | GBA1 (0.46) | VDRALDH1A1KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165110-A1 | Optically active isocarbostyril derivatives and a method of preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1985-12-18 | — | — | EP | disclosed |