Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021295 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11022404 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11020875 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11021287 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11019851 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11019158 | 0.85 | PDE3B (0.45) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL9478348 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11024452 | 0.84 | KMT2A (0.48) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11019337 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1RXFP1 | |
| SCHEMBL11024729 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |