Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021287 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL11022404 | 0.96 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL11021295 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL11020201 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9475164 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9475528 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9476379 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9477002 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL10746252 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9475251 | 0.82 | KDM4E (0.46) | ALDH1A1KDM4EHPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |