Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543818 | 0.85 | F7 (0.53) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27601968 | 0.85 | F7 (0.53) | F7F3SARM1SIRT2SIRT6 | |
| Hydrochloric Acid SCHEMBL2821000 | 0.83 | F7 (0.51) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27576449 | 0.83 | ALDH1A1 (0.53) | F7F3SARM1SIRT2SIRT6 | |
| Niacin SCHEMBL10620476 | 0.82 | ALDH1A1 (0.66) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27780057 | 0.82 | F7 (0.62) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27951597 | 0.81 | TBXAS1 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL28659975 | 0.80 | F7 (0.60) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL10620479 | 0.80 | ALDH1A1 (0.51) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL717650 | 0.80 | GRM8 (0.49) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161422-A1 | Alkanolamine derivatives and platelet aggregation inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-11-21 | — | — | EP | disclosed |