SCHEMBL110207

SCHEMBL110207

Brc1ccc2nc[nH]c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.59
QPCT Q16769 3/20 0.57
KDM4E B2RXH2 4/20 0.57
MAPT P10636 3/20 0.57
RAD52 P43351 1/20 0.57
CHEK1 O14757 1/20 0.56
PIM1 P11309 1/20 0.56
AKT1 P31749 1/20 0.56
FLT3 P36888 1/20 0.56
PIM3 Q86V86 1/20 0.56
MMP12 P39900 1/20 0.53
CYP3A4 P08684 2/20 0.52
NAMPT P43490 1/20 0.52
XDH P47989 1/20 0.52
HDAC6 Q9UBN7 1/20 0.51
P2RY6 Q15077 1/20 0.48
P2RY14 Q15391 1/20 0.48
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
APEX1 P27695 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467513 1.00 PRKCI (0.59) PRKCIQPCTKDM4EMAPTRAD52
Hydrochloric Acid SCHEMBL16011437 0.98 KDM4E (0.60) PRKCIQPCTKDM4EMAPTRAD52
SCHEMBL29908911 0.83 CHEK1 (0.52) PRKCIQPCTKDM4EMAPTRAD52
SCHEMBL10757 0.83 CHEK1 (0.52) PRKCIQPCTKDM4EMAPTRAD52
SCHEMBL28178104 0.80 QPCT (0.60) PRKCIQPCTKDM4EMAPTRAD52
SCHEMBL28076069 0.79 QPCT (0.55) PRKCIQPCTKDM4EMAPTRAD52
Benzimidazole SCHEMBL26920544 0.79 CHEK1 (0.45) PRKCIQPCTKDM4EMAPTRAD52
SCHEMBL8634290 0.77 QPCT (0.68) PRKCIQPCTKDM4EMAPTRAD52
SCHEMBL20644661 0.76 KDM4E (0.52) PRKCIQPCTKDM4EMAPTALDH1A1
SCHEMBL4740277 0.74 PRKCI (0.59) PRKCIQPCTKDM4EMAPTRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE Shanghai OuChem Bio-Technology Co., LTD (CN) 2026-04-23 US claimed
CN-118581738-A Preparation method of patterned local super-hydrophobic breathable cotton fabric based on ink-jet printing technology 青岛大学 2024-09-03 CN claimed
CN-116143414-B Preparation method of vitrified ZIF-300 material 天津工业大学 2024-08-09 CN claimed
CN-118344611-A Method for preparing micro-nano metal organic framework by oil-water two-phase method and application 广西师范大学 2024-07-16 CN claimed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP claimed
CN-116143414-A Preparation method of vitrified ZIF-300 material 天津工业大学 2023-05-23 CN claimed
CN-114870650-B Zinc-based MOF membrane material with interpenetrating composite structure, and preparation method and application thereof 南京工业大学 2023-05-05 CN claimed
CN-115646454-A Hierarchical pore ZIFs material and low-temperature plasma preparation method and application thereof 华南理工大学 2023-01-31 CN claimed
CN-114870650-A Zinc-based MOF (Metal-organic framework) membrane material with interpenetrating composite structure as well as preparation method and application thereof 南京工业大学 2022-08-09 CN claimed
CN-113368253-B Drug carrier based on zeolite imidazole framework structure and preparation method and application thereof 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 2022-06-10 CN claimed
CN-108951158-B Nano composite fiber membrane and preparation method thereof 厦门理工学院 2021-05-28 CN claimed
EP-3774001-A1 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2021-02-17 EP claimed
US-20210016232-A1 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES EVOVE LTD (GB) 2021-01-21 US claimed
CN-107955020-B Method for synthesizing benzimidazol oxazinone compound by copper salt catalysis in one pot 西南大学 2020-09-22 CN claimed
CN-111253580-A Preparation method of tubular MOF (Metal organic framework) membrane 中国科学院大连化学物理研究所 2020-06-09 CN claimed
US-10086331-B2 Carbon dioxide capture using phase change ionic liquids UNIVERSITY OF NOTRE DAME DU LAC (US) 2018-10-02 US claimed
US-20160288051-A1 CARBON DIOXIDE CAPTURE USING PHASE CHANGE IONIC LIQUIDS UNIVERSITY OF NOTRE DAME DU LAC (US) 2016-10-06 US claimed
US-20140031289-A1 POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-01-30 US claimed
WO-2011033235-A1 COMPOSITE MATERIAL COMPRISING AN ORGANIC-INORGANIC MATERIAL, PREPARATION PROCESS, AND USES TREDI (FR) 2011-03-24 WO claimed
US-4105656-A PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031289-A1 POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF PHOSPHO1, PLCB3, INPP5D PRKCI 680/4885QPCT 1270/4885KDM4E 1770/4885
US-20260109670-A1 METHOD FOR ARYL DEBROMINATION AND ACYLATION OF BROMINATED BENZO-FUSED NITROGEN HETEROCYCLE NAT1, AADAC, NAA15 PRKCI 4130/4885QPCT 1071/4885KDM4E 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.