SCHEMBL28076069

SCHEMBL28076069

Brc1cc(Br)cc(-c2ccc3nc[nH]c3c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 7/20 0.55
QPCTL Q9NXS2 4/20 0.55
PRKCI P41743 2/20 0.50
KDM4E B2RXH2 3/20 0.49
MAPT P10636 2/20 0.49
RAD52 P43351 1/20 0.49
PSMD11 O00231 1/20 0.48
BRD4 O60885 1/20 0.48
CREBBP Q92793 1/20 0.48
NPC1 O15118 2/20 0.47
ALDH1A1 P00352 2/20 0.47
TP53 P04637 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HPGD P15428 1/20 0.47
MMP12 P39900 1/20 0.46
HDAC6 Q9UBN7 1/20 0.45
CYP3A4 P08684 1/20 0.45
NAMPT P43490 1/20 0.45
XDH P47989 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634290 0.87 QPCT (0.68) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL28178104 0.86 QPCT (0.60) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL28076068 0.86 QPCT (0.41) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL2474515 0.79 QPCT (0.60) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL29467513 0.79 PRKCI (0.59) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL110207 0.79 PRKCI (0.59) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL28190281 0.79 QPCT (0.64) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL2462345 0.78 QPCT (0.68) QPCTQPCTLPRKCIKDM4EMAPT
Hydrochloric Acid SCHEMBL16011437 0.77 KDM4E (0.60) QPCTQPCTLPRKCIKDM4EMAPT
SCHEMBL38665709 0.76 QPCT (0.66) QPCTQPCTLPRKCIKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315840-A 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2022-04-12 CN disclosed
CN-106188065-B 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2021-12-28 CN disclosed
CN-108440531-A 4H- imidazos [1,2-a] imidazoles for electronic application UDC 爱尔兰有限责任公司 2018-08-24 CN disclosed
CN-108299439-A 4H- imidazos [1,2-a] imidazoles for electronic application UDC 爱尔兰有限责任公司 2018-07-20 CN disclosed
CN-103917542-B 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2018-03-27 CN disclosed
CN-106188065-A 4H imidazo [1,2 a] imidazoles for electronic application 巴斯夫欧洲公司 2016-12-07 CN disclosed
CN-103517906-B 4H-imidazo [1,2-a ] imidazoles for electronic applications 巴斯夫欧洲公司 2016-08-24 CN disclosed