Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475164 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9477002 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9476379 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9475251 | 0.96 | KDM4E (0.46) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9476022 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL10805720 | 0.85 | PDE3B (0.45) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL9478348 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL11021287 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL11020875 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAHPGDPOLB | |
| SCHEMBL11022404 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124089-B1 | NOVEL 5-ACYL-2-(1H)-PYRIDINONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-04 | — | — | EP | claimed |
| US-5212314-A | Alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-05-18 | — | — | US | disclosed |
| US-5212315-A | Alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0140375-B1 | ALKOXYIMINO ETHER DERIVATIVES OF 5-ACYL-2(1H)-PYRIDINONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| US-5043449-A | Certain alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-27 | — | — | US | disclosed |
| US-4920229-A | Novel alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849522-A | Novel alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS (US) | 1989-07-18 | — | — | US | disclosed |
| US-4732982-A | Novel alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0124089-B1 | NOVEL 5-ACYL-2-(1H)-PYRIDINONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4568751-A | 5-Acyl-2-(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-02-04 | — | — | US | disclosed |
| EP-0140375-A2 | Alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-05-08 | — | — | EP | disclosed |
| EP-0124089-A1 | Novel 5-acyl-2-(1H)-pyridinones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-11-07 | — | — | EP | disclosed |