Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GSDMD | P57764 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498253 | 0.84 | HSD17B10 (0.37) | HSD17B10ABCB11CYP2E1PTGS1HTT | |
| SCHEMBL11020886 | 0.81 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL3920815 | 0.75 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL3911408 | 0.74 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL3910217 | 0.71 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL10748425 | 0.71 | HSD17B10 (0.37) | HSD17B10PHGDH | |
| SCHEMBL21219160 | 0.70 | L3MBTL1 (0.36) | SIGMAR1HSD17B10 | |
| SCHEMBL3910211 | 0.70 | GNAI3 (0.40) | SIGMAR1 | |
| SCHEMBL3912620 | 0.70 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL10643920 | 0.70 | SIGMAR1 (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029998-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-06 | — | — | EP | disclosed |