SCHEMBL11021065

SCHEMBL11021065

CCN1CC(=O)N(c2ccc(C(=O)O)cc2)C1=S

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA9 Q16790 3/20 0.51
SMN1; SMN2 Q16637 5/20 0.45
GAA P10253 1/20 0.45
RECQL P46063 1/20 0.45
DDAH1 O94760 1/20 0.45
LMNA P02545 4/20 0.44
POLB P06746 1/20 0.44
CA2 P00918 2/20 0.42
SCN2A Q99250 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032861 0.83 KMT2A (0.63) KMT2AMEN1L3MBTL1SMN1; SMN2GAA
SCHEMBL11024739 0.79 KMT2A (0.45) KMT2AMEN1L3MBTL1SMN1; SMN2GAA
SCHEMBL1303806 0.78 CA12 (0.56) L3MBTL1CA12CA1CA9GAA
SCHEMBL11638136 0.77 NPC1 (0.56) KMT2AMEN1L3MBTL1CA12CA1
SCHEMBL8698116 0.73 KMT2A (0.52) KMT2AMEN1L3MBTL1SMN1; SMN2GAA
SCHEMBL7813288 0.72 KMT2A (0.53) KMT2AMEN1L3MBTL1SMN1; SMN2GAA
SCHEMBL6740798 0.70 KMT2A (0.71) KMT2AMEN1L3MBTL1CA12CA1
SCHEMBL11692626 0.69 KMT2A (0.50) KMT2AMEN1L3MBTL1SMN1; SMN2GAA
SCHEMBL10784216 0.69 KMT2A (0.75) KMT2AMEN1L3MBTL1SMN1; SMN2GAA
SCHEMBL458085 0.69 CA12 (1.00) KMT2AMEN1L3MBTL1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048834-B1 METHOD FOR MEASUREMENT OF TRACE ENZYMES FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed
EP-0047470-B1 METHOD FOR IMMUNOCHEMICAL MEASUREMENT FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
US-4473652-A LABELLING WITH CYANINE OR MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047470-A1 Method for immunochemical measurement FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed