Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685398 | 0.87 | KMT2A (0.56) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11142249 | 0.84 | CMA1 (0.59) | NPC1RAB9AKMT2ACA12CA1 | |
| SCHEMBL11065342 | 0.81 | HTT (0.53) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL11072116 | 0.81 | KMT2A (0.49) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL1303806 | 0.80 | CA12 (0.56) | CA12CA1CA9CA2SCN2A | |
| SCHEMBL11147745 | 0.79 | DUSP22 (0.47) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL5955047 | 0.79 | KMT2A (0.56) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL5955129 | 0.79 | PLCG1 (0.55) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5955275 | 0.79 | KMT2A (0.56) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL11071726 | 0.78 | CTSG (0.51) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108667-A | Photographic compositions and elements containing benzo[a]quinolizinium methine dyes | EASTMAN KODAK COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4003750-A | METHINE DYES | EASTMAN KODAK COMPANY (US) | 1977-01-18 | — | — | US | disclosed |