Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224186 | 0.82 | ENPP2 (0.49) | KMT2AMEN1CYP3A4POLBHSP90AA1 | |
| SCHEMBL6032861 | 0.82 | KMT2A (0.63) | KMT2AMEN1CYP3A4POLBLMNA | |
| SCHEMBL8663397 | 0.77 | KMT2A (0.53) | KMT2AMEN1CYP3A4POLBLMNA | |
| SCHEMBL6031707 | 0.75 | KMT2A (0.54) | KMT2AMEN1POLBLMNAALDH1A1 | |
| SCHEMBL8475279 | 0.74 | KMT2A (0.60) | KMT2AMEN1LMNAGAASMN1; SMN2 | |
| SCHEMBL11021065 | 0.73 | KMT2A (0.53) | KMT2AMEN1CYP3A4POLBLMNA | |
| SCHEMBL8666034 | 0.73 | KMT2A (0.50) | KMT2AMEN1POLBLMNAALDH1A1 | |
| SCHEMBL8475297 | 0.72 | GAA (0.64) | KMT2AMEN1LMNAGAASMN1; SMN2 | |
| SCHEMBL8475522 | 0.72 | FAAH (0.49) | KMT2AMEN1LMNAALDH1A1GAA | |
| SCHEMBL9013774 | 0.71 | MEN1 (0.60) | KMT2AMEN1CYP3A4LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783707-A | ANTICHOLESTEROL AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |