Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778039 | 0.78 | HSD17B10 (0.65) | MAPTS1PR1S1PR3KDM4ENPC1 | |
| SCHEMBL11021395 | 0.77 | NQO1 (0.52) | MAPTTP53KDM4ENPC1HSD17B10 | |
| SCHEMBL6013688 | 0.77 | MKNK1 (0.51) | MAPTTP53RXFP1PTPRCRAB9A | |
| SCHEMBL3883588 | 0.77 | MEN1 (0.51) | MAPTTP53RXFP1PTPRCKDM4E | |
| SCHEMBL27814160 | 0.77 | KDM4E (0.60) | MAPTTP53RXFP1S1PR1KDM4E | |
| SCHEMBL11017769 | 0.77 | RXRA (0.51) | MAPTTP53KDM4EHSD17B10KMT2A | |
| SCHEMBL28554230 | 0.75 | PDK2 (0.47) | MAPTTP53KDM4ENPC1HSD17B10 | |
| SCHEMBL22381396 | 0.74 | PGR (0.67) | PGRARMAPTTP53KDM4E | |
| SCHEMBL22381391 | 0.74 | PGR (0.62) | PGRARMAPTTP53KDM4E | |
| SCHEMBL4744927 | 0.72 | MEN1 (0.48) | MAPTTP53PTPRCKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |