Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023442 | 0.84 | PTGER2 (0.61) | PTGER2PTGER3PTGDRPTGER4ALDH1A1 | |
| SCHEMBL17501926 | 0.81 | PTGER2 (0.44) | PTGER2PTGER3PTGDRP2RX7MTNR1A | |
| SCHEMBL16096237 | 0.81 | PTGER2 (0.44) | PTGER2PTGER3PTGDRP2RX7MTNR1A | |
| SCHEMBL9892975 | 0.78 | PTGER2 (0.44) | PTGER2PTGER3PTGDRP2RX7MTNR1A | |
| SCHEMBL1310058 | 0.77 | PTGER2 (1.00) | PTGER2PTGER3PTGDRPTGER1PTGER4 | |
| SCHEMBL2992422 | 0.77 | PTGER2 (1.00) | PTGER2PTGER3PTGDRPTGER1PTGER4 | |
| SCHEMBL1310059 | 0.77 | PTGER2 (1.00) | PTGER2PTGER3PTGDRPTGER1PTGER4 | |
| SCHEMBL10782534 | 0.77 | L3MBTL1 (0.46) | PTGER2PTGER3KDM4EALDH1A1 | |
| SCHEMBL10475651 | 0.77 | PTGER4 (0.46) | PTGER2PTGER3P2RX7MTNR1APTGER4 | |
| SCHEMBL28997140 | 0.74 | PTGER2 (0.39) | PTGER2PTGER3PTGDRP2RX7MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164853-A1 | (substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids, a process for producing the compounds and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-12-18 | — | — | EP | claimed |