SCHEMBL11021802

SCHEMBL11021802

CCc1ccc(-c2c(Cl)ccc3[nH]nnc23)c(O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.38
GSK3B P49841 1/20 0.33
DAO P14920 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
PAX8 Q06710 1/20 0.32
PTGES O14684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HSP90AA1 P07900 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
ALOX15 P16050 2/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27447008 0.79 BRAF (0.34) GAA
SCHEMBL6064915 0.78 MEN1 (0.39) MEN1KMT2AGAAALOX15NPC1
SCHEMBL30117209 0.78 MEN1 (0.39) MEN1KMT2AGAAALOX15NPC1
SCHEMBL8773836 0.78 BACE1 (0.39) GAACYP2C9CNR1CNR2ALOX15
SCHEMBL8847324 0.76 IDO1 (0.38) MEN1KMT2APOLBGAAHSP90AA1
SCHEMBL8773777 0.76 IGF1R (0.38) GAACYP2C9CNR1CNR2ALOX15
SCHEMBL8773796 0.74 FFAR1 (0.45)
SCHEMBL31570221 0.73 ALDH1A1 (0.37) MEN1KMT2AGAACYP2C9ALOX15
SCHEMBL11075897 0.73 ALDH1A1 (0.37) MEN1KMT2AGAACYP2C9ALOX15
SCHEMBL3177695 0.72 AMY1A (0.35) MEN1KMT2AGAACYP2C9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164223-A2 Method for dyeing polyester fiber materials SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-11 EP disclosed