SCHEMBL8847324

SCHEMBL8847324

Cc1ccc(O)c(-c2c(Cl)ccc3[nH]nnc23)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
HPGD P15428 9/20 0.37
MEN1 O00255 9/20 0.37
KMT2A Q03164 9/20 0.37
MAPT P10636 10/20 0.36
NT5E P21589 1/20 0.36
ALOX15 P16050 5/20 0.36
USP2 O75604 3/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
NFKB1 P19838 2/20 0.35
NFKB2 Q00653 2/20 0.35
RELA Q04206 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551678 0.88 IDO1 (0.38) IDO1HPGDMEN1KMT2AMAPT
SCHEMBL8654068 0.86 MEN1 (0.41) IDO1HPGDMEN1KMT2AMAPT
SCHEMBL31570221 0.83 ALDH1A1 (0.37) IDO1HPGDMEN1KMT2AMAPT
SCHEMBL11075897 0.83 ALDH1A1 (0.37) IDO1HPGDMEN1KMT2AMAPT
SCHEMBL31621073 0.83 TRPA1 (0.31)
SCHEMBL7129918 0.81 ESR2 (0.44) HPGDMEN1KMT2AMAPTALOX15
SCHEMBL27447008 0.81 BRAF (0.34) IDO1GAA
SCHEMBL6064915 0.80 MEN1 (0.39) IDO1HPGDMEN1KMT2AMAPT
SCHEMBL30117209 0.80 MEN1 (0.39) IDO1HPGDMEN1KMT2AMAPT
SCHEMBL3177695 0.80 AMY1A (0.35) HPGDMEN1KMT2AMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111542568-B Resin composition and method for producing same 株式会社可乐丽 2023-04-14 CN disclosed
CN-115505220-A Resin composition, multilayer structure, light conversion film, and agricultural film 苏州睿尔思科技有限公司 2022-12-23 CN disclosed
CN-111542568-A Resin composition, process for producing the same, molded article, multilayer structure, film, process for producing the same, vapor-deposited film, packaging material, vacuum packaging bag, vacuum insulator, thermoformed container, blow-molded container, fuel container, and bottle container 株式会社可乐丽 2020-08-14 CN disclosed
EP-0782598-A1 STABILIZED FILLED POLYOLEFINS Ciba SC Holding AG (CH) 1997-07-09 EP disclosed