Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264573 | 0.88 | LMNA (0.53) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL7432301 | 0.88 | LMNA (0.53) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL6265451 | 0.86 | L3MBTL1 (0.46) | ABCB11LMNAMAPTMAPK1PPARA | |
| SCHEMBL7433095 | 0.86 | LMNA (0.53) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11205593 | 0.86 | HDAC1 (0.41) | MAPTPPARAMEN1KMT2AEPHX2 | |
| SCHEMBL6262433 | 0.85 | MAPT (0.68) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL6550151 | 0.85 | GAA (0.56) | ABCB11LMNAMAPTMAPK1MAOB | |
| SCHEMBL6262992 | 0.85 | MAPT (0.68) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL6263163 | 0.85 | MAPT (0.52) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL7426444 | 0.85 | MAPT (0.52) | ABCB11LMNAMAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |
| WO-1982000643-A1 | SUBSTITUTED OXIRANECARBONIC ACIDS,PREPARATION AND PHARMACEUTICAL UTILISATION THEREOF | BYK GULDEN LOMBERG CHEM FAB (DE) | 1982-03-04 | — | — | WO | disclosed |