Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060937 | 0.81 | CSF1R (0.58) | CSF1RALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11016941 | 0.79 | CSF1R (0.57) | CSF1RALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27534143 | 0.79 | CSF1R (0.47) | CSF1RALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27534146 | 0.79 | CSF1R (0.47) | CSF1RALDH1A1KDM4EHPGDPKM | |
| SCHEMBL6105948 | 0.74 | CSF1R (0.51) | CSF1RSMN1; SMN2RAB9ANPC1HSD17B10 | |
| SCHEMBL26790051 | 0.72 | P2RX7 (0.39) | — | |
| SCHEMBL26792058 | 0.70 | PKM (0.49) | ALDH1A1KDM4EHPGDPKMSMN1; SMN2 | |
| SCHEMBL26789538 | 0.70 | NPSR1 (0.47) | ALDH1A1KDM4EHPGDPKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1448612 | 0.69 | CSF1R (0.39) | CSF1RALDH1A1HSD17B10 | |
| SCHEMBL17251487 | 0.68 | LMNA (0.49) | ALDH1A1KDM4EHPGDPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-1649863-A | 4- (imidazol-5-yl) -2- (4-sulfoanilino) pyrimidine derivatives having CDK inhibitory activity | ASTRAZENECA AB (SE) | 2005-08-03 | — | — | CN | disclosed |
| EP-0156644-A1 | Process and intermediates for 4-acetylimidazoles | PFIZER INC. (US) | 1985-10-02 | — | — | EP | disclosed |