Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022084 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1GAAMRGPRX4LMNA | |
| SCHEMBL11017742 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1GAAMRGPRX4LMNA | |
| SCHEMBL6265451 | 0.90 | L3MBTL1 (0.46) | KDM4EALDH1A1GAAMRGPRX4LMNA | |
| SCHEMBL11210108 | 0.83 | HDAC1 (0.47) | KDM4EGAALMNAMAOBKMT2A | |
| SCHEMBL11206711 | 0.83 | HDAC1 (0.47) | KDM4EGAALMNAMAOBKMT2A | |
| SCHEMBL11020225 | 0.83 | L3MBTL1 (0.47) | KDM4EALDH1A1GAAMRGPRX4LMNA | |
| SCHEMBL11290182 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1GAAMRGPRX4LMNA | |
| SCHEMBL11295569 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1GAAMRGPRX4LMNA | |
| SCHEMBL7431979 | 0.81 | HDAC1 (0.41) | KDM4ELMNAHTTUSP2ALOX5 | |
| SCHEMBL6264086 | 0.79 | MRGPRX4 (0.52) | KDM4EALDH1A1GAAMRGPRX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |