Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206711 | 1.00 | HDAC1 (0.47) | HDAC1HDAC8KDM4EMEN1KMT2A | |
| SCHEMBL7431979 | 0.90 | HDAC1 (0.41) | HDAC1HDAC8KDM4EMEN1KMT2A | |
| SCHEMBL7428692 | 0.86 | ALDH1A1 (0.41) | HDAC1HDAC8KDM4EMEN1KMT2A | |
| SCHEMBL11209089 | 0.85 | HDAC1 (0.49) | HDAC1HDAC8KDM4EMEN1KMT2A | |
| SCHEMBL11020231 | 0.85 | HDAC1 (0.40) | HDAC1HDAC8KMT2AMAOBGAA | |
| SCHEMBL11203221 | 0.85 | THRB (0.43) | HDAC1HDAC8KDM4EMEN1KMT2A | |
| SCHEMBL11205182 | 0.84 | NAAA (0.42) | KDM4EMAOBGAAMTNR1AMTNR1B | |
| SCHEMBL11017742 | 0.84 | KDM4E (0.48) | KDM4EKMT2ALMNAMAOBGAA | |
| SCHEMBL11022084 | 0.84 | KDM4E (0.48) | KDM4EKMT2ALMNAMAOBGAA | |
| SCHEMBL11018161 | 0.83 | ALDH1A1 (0.40) | HDAC1HDAC8KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |