Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021232 | 0.92 | SERPINA6 (0.50) | SERPINA6CYP19A1SHBGLMNAALDH1A1 | |
| SCHEMBL11022543 | 0.81 | SERPINA6 (0.47) | SERPINA6CYP19A1SHBGLMNAALDH1A1 | |
| SCHEMBL11019743 | 0.80 | SERPINA6 (0.70) | SERPINA6CYP19A1SHBGLMNAALDH1A1 | |
| SCHEMBL11024872 | 0.80 | ALDH1A1 (0.58) | SERPINA6CYP19A1SHBGLMNAALDH1A1 | |
| SCHEMBL11022656 | 0.77 | LMNA (0.57) | CYP19A1SHBGLMNAALDH1A1CYP3A4 | |
| SCHEMBL5072793 | 0.74 | ALDH1A1 (0.56) | SERPINA6SHBGLMNAALDH1A1CYP3A4 | |
| SCHEMBL19028027 | 0.72 | LMNA (0.74) | SERPINA6SHBGLMNAALDH1A1CYP3A4 | |
| SCHEMBL11595725 | 0.72 | LMNA (0.74) | SERPINA6SHBGLMNAALDH1A1CYP3A4 | |
| SCHEMBL11024870 | 0.72 | ALDH1A1 (0.56) | SERPINA6SHBGLMNAALDH1A1CYP3A4 | |
| SCHEMBL11020224 | 0.71 | SERPINA6 (0.62) | SERPINA6CYP19A1SHBGLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054786-B1 | 6-ALPHA-METHYL HYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND THEIR UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0054786-B1 | 6-ALPHA-METHYL HYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND THEIR UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |