Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.57 |
| ▸ | PGR | P06401 | 3/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020866 | 0.92 | PGR (0.60) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL3973882 | 0.84 | LMNA (0.75) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL10703743 | 0.83 | NR3C1 (0.53) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL10706361 | 0.82 | CYP3A4 (0.56) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL11511438 | 0.81 | LMNA (0.78) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL11511435 | 0.81 | LMNA (0.78) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL8938537 | 0.79 | LMNA (0.54) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL11702055 | 0.79 | LMNA (0.54) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL10705558 | 0.79 | NR3C1 (0.52) | LMNACYP3A4NR3C1PGRNR3C2 | |
| SCHEMBL11021243 | 0.79 | CYP3A4 (0.73) | LMNACYP3A4NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054786-B1 | 6-ALPHA-METHYL HYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND THEIR UTILIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |